Research finds evidence to suggest Pacific whiting skin has anti-aging properties that prevent wrinkles
The gelatin in the skin of Pacific whiting, a common fish on the Pacific coast of North America, may help prevent skin wrinkles caused by ultraviolet radiation, a new study from Oregon State University finds.
Pacific whiting is widely caught in the United States, but consumers are not very familiar with the mild, white-fleshed fish, also known as hake. However, it is popular in Europe, where it is the eighth most consumed variety. In the US, the 10 most consumed species account for 77% of total seafood consumption per capita, and Pacific whiting is not in the top 10.
By studying Pacific whiting. Jung Kwon, an assistant professor at Oregon State Seafood Research & Education Center in Astoria, Oregon, wants to change that and ease the pressure on stocks of those 10 species, including salmon and tuna.
She studies marine organisms and their potential to improve human health, and is particularly interested in the benefits of parts of marine organisms such as fish skin, which many American consumers prefer to throw away rather than eat.
“Fish skins are an abundant resource that we already know have valuable nutritional properties,” Kwon said. “But we wanted to know what additional potential value could be found in something traditionally thought of as a by-product.”
In an article recently published in the magazine marine drugsKwon and a team of researchers looked at molecular pathways that contribute to wrinkling at the cellular level. Those wrinkles are promoted by chronic exposure to ultraviolet light, which breaks down collagen in the skin.
The researchers extracted gelatin from Pacific whiting fish and then looked at its impact on antioxidants and inflammatory responses and pathways known to break down collagen and promote collagen synthesis.
They found that the Pacific whiting skin:
- Reactivated to a certain level the collagen synthesis pathway that had been suppressed by UV radiation.
- Prevented activation to a certain level of the collagen degradation pathway accelerated by UV radiation.
- Promoted additional antioxidant activity. Antioxidants are substances that can prevent or slow down damage to cells.
- Promoted additional anti-inflammatory effects.
Kwon warned that these are the first results obtained in her lab using a human cell model system. Further research is needed using animal models.
“We saw some potential with a positive response in the cell model system,” she said. “This gives us good evidence to take those next steps.”
Study shows new potential of fish byproducts
Seok Hee Han et al, Anti-photoaging effect of Pacific Whiting Skin hydrolysates via MAPK/AP-1, NF-KB, TGF-β/Smad and Nrf-2/HO-1 signaling pathway in UVB-induced human dermal fibroblasts , marine drugs (2022). DOI: 10.3390/md20050308
Quote: Study finds evidence suggesting Pacific whiting skin has anti-aging properties that prevent wrinkles (2022, June 21) retrieved June 21, 2022 from https://phys.org/news/2022-06-evidence-pacific- whiting-skin- anti-aging.html
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