Home US Police are questioning Charlie Sheen’s ex Brooke Mueller over the ketamine death of Matthew Perry, as investigators say “several people” may be charged.

Police are questioning Charlie Sheen’s ex Brooke Mueller over the ketamine death of Matthew Perry, as investigators say “several people” may be charged.

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Brooke Mueller, 46, was married to troubled actor Charlie Sheen between 2008 and 2011, and the couple has three children together.

Charlie Sheen’s ex-wife Brooke Mueller has been interviewed “multiple times” by Los Angeles police in connection with Matthew Perry’s death after the couple reportedly bonded during their rehab stays, according to a new report.

Mueller was never arrested or handcuffed in connection with the investigations, sources said. In contact who has been cooperating with the criminal investigation.

“He has hired lawyers and has had multiple meetings with law enforcement since they arrived at his halfway house with a search warrant. He hasn’t said anything about the situation,” a source told the magazine.

This development comes after an independent report was released that said investigators could charge “several people” in connection with the actor’s death. DailyMail.com has contacted Mueller for comment on this story.

“It’s hard to say or know exactly what her role (in Matthew’s death) is, but she insists she had nothing to do with it.”

Mueller, 46, has had several substance abuse problems over the years. In July 2011, she underwent a rehabilitation program. Two years later, her children were removed from her home for suspected drug use. Mueller re-entered rehab at that time.

Brooke Mueller, 46, was married to troubled actor Charlie Sheen between 2008 and 2011, and the couple has three children together.

Matthew Perry photographed in his hot tub in his last Facebook post before his death in October 2023.

Matthew Perry photographed in his hot tub in his last Facebook post before his death in October 2023.

Perry, shown here in 2015, died from the 'acute effects of ketamine,' according to an autopsy

Perry, shown here in 2015, died from the ‘acute effects of ketamine,’ according to an autopsy

Her last period of public rehab occurred in August 2019. Between 2008 and 2011, Mueller was married to actor Charlie Sheen. The couple has twin sons, Bob and Max. Their divorce came amid allegations of domestic abuse by Sheen.

Perry’s death in October 2023 at the age of 54 shocked the world. The beloved Friends star was unresponsive in the hot tub at her Los Angeles home. An autopsy attributed her death to the “acute effects of ketamine.”

The amount of ketamine in his blood was in the range used for general anesthesia during surgery. It was listed as the primary cause of death, which was ruled an accident with no suspicion of foul play, according to the report.

People close to the actor told forensic investigators that he was receiving ketamine infusion therapy. This decades-old surgical drug has seen a huge increase in use in recent years as a treatment for depression, anxiety and pain.

According to the InTouch report, investigators in the case confiscated a laptop and an iPhone from Mueller.

A close source confirmed to InTouch that Mueller and Perry met during rehab. “They struck up an unexpected friendship,” the friend said.

Perry said in 2022 that he estimated he spent $9 million fighting his addictions during 15 rehab stays.

In a report of People released Tuesday, a law enforcement investigative source said the investigation is now “closer to a conclusion.”

Brooke Mueller poses for her mugshot after being arrested and charged with assault and possession of cocaine with intent to distribute on December 3, 2011.

Brooke Mueller poses for her mugshot after being arrested and charged with assault and possession of cocaine with intent to distribute on December 3, 2011.

Mueller has spent multiple stints in rehab, the most recent occurring in 2019.

Mueller has spent multiple stints in rehab, the most recent occurring in 2019.

The source did not clarify who the “multiple people” potentially facing charges are, adding that any future action will ultimately be determined by the U.S. Attorney’s Office.

However, in December of last year, a medical expert speculated to Page Six that the actor had “probably” obtained ketamine illegally for “recreational use.”

Although Perry was receiving ketamine treatment for anxiety and depression at the time of his death, his autopsy report noted that “the ketamine in his system at the time of his death could not have come from that infusion therapy.”

Working with the DEA and the US Postal Inspector, the LAPD began investigating where the ketamine that “ended up playing a role” in the actor’s death came from.

At the time, TMZ reported that an ongoing investigation was seeking to deduce where the actor, who spent years battling alcoholism and drug addiction, obtained ketamine.

“Law enforcement sources tell us there is an ongoing investigation into where Matthew obtained the ketamine that ended up playing a role in his death, and the main questions are who provided the drug and under the circumstances,” the outlet reported.

Sources also told the outlet that “both local police and the DEA have been investigating this matter for months, but it is unclear where exactly investigators are in the investigation.”

It was also revealed that they had already spoken to “some key people in Hollywood,” who “are known to have a history of drug use or abuse,” as they “could have information leading to the source,” according to the report.

A year before her death, she opened up about her struggle with addiction and detailed her journey to sobriety in her memoir Friends, Lovers, and the Big Terrible Thing.

In the tell-all report released in 2022, he claimed he was finally sober after multiple failed attempts at detox and at a personal cost of $9 million.

Sources later told DailyMail.com that the ‘lonely’ star would have younger connections with dating app Raya to deliver drugs to her home even while she was under the care of a 24/7 nursing team of the week.

Despite having a nursing staff in his $6 million Pacific Palisades home, as well as a sober partner living there, Perry managed to have chance encounters that introduced illicit drugs to him undetected, sources explained in December 2023.

“He met girls on dating apps and invited them to come,” insiders claimed.

‘There were a lot of young people aged between 21 and 25 that I would meet in Raya. They would bring drugs with them. It was mainly Oxycontin (a powerful opioid pain reliever). He also got illicit drugs from old girlfriends, there was some kind of network,” a source said.

The source added: “I think with (his memoir), Matthew thought it would help him get to the place he was describing.

‘I was writing about what I hoped the situation would be like it was already there. She was writing the script she wanted.”

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