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Women who are treated twice as often for early breast cancer will develop and die of the disease years later

Women treated for early breast cancer are twice as likely to develop and die from the disease until 20 years later, new research shows

  • Cancer cells in milk ducts are considered treatable and non-life threatening
  • Researchers wanted to determine the long-term risk for women with the diagnosis
  • Most women with DCIS are recalled for annual mammograms for only five years

Women treated for early breast cancer are twice as likely to develop and die from an aggressive form of the disease until 20 years later, a study found.

Ductal carcinoma in situ (DCIS) – cancer cells in the milk ducts – is considered treatable and non-life threatening. But researchers wanted to determine the long-term risk for women with the diagnosis.

They looked at 35,024 women in England who were diagnosed with DCIS through the NHS breast screening program from its inception in 1988 to March 2014.

By December 2014, 2,076 women had developed invasive breast cancer – an incidence of 8.82 per 1,000 per year – and more than double the expected national rate.

Ductal carcinoma in situ (DCIS) - cancer cells in the milk ducts - is considered treatable and non-life threatening. But researchers wanted to determine the long-term risk for women diagnosed (stock image)

Ductal carcinoma in situ (DCIS) – cancer cells in the milk ducts – is considered treatable and non-life threatening. But researchers wanted to determine the long-term risk for women diagnosed (stock image)

About 310 died of breast cancer – a death rate of 1.26 per 1,000 per year and 70 percent more than expected from national rates.

For both invasive breast cancer and death from breast cancer, the increases persisted for at least two decades, the BMJ reported.

However, most women with DCIS are recalled from annual mammograms for only five years. They are followed up every three years until the age of 70.

Professor Sarah Darby, from the University of Oxford, who led the study, said, “Understanding more about this risk will allow us to make more informed decisions about how to treat and monitor women with DCIS to give them the best possible care. and save lives. “

Most women with DCIS are only recalled for annual mammograms for five years (stock image)

Most women with DCIS are only recalled for annual mammograms for five years (stock image)

Most women with DCIS are recalled for annual mammograms for only five years (stock image)

Research author Dr Gurdeep Mannu, of the University of Oxford, said: “We have shown that women diagnosed with DCIS detected by screening in England have experienced a significantly increased risk of both invasive breast cancer and death from breast cancer compared to women in the United States. general population, despite lower overall mortality.

Screened-detecting women with DCIS showed both invasive breast cancer and breast cancer mortality, which were more than double that of the general population from several years after being diagnosed with DCIS, and the increase lasted until at least 20 years after diagnosis.

“The increases affected women of all ages.”

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