What is the Difference Between Synthesis and Biosynthesis?

Synthesis and Biosynthesis

The polymerization of small subunits generates the macromolecules. Carbohydrates, lipids, proteins, plastics, nucleic acids, silk, rubber, etc., are widely called macromolecules. Few macromolecules are organic, and others are synthetic. Some are organic compounds, and others are not organic. The creation of macromolecules by mixing single or tiny molecules is known as synthesis.

A bio synthesis is a form of synthesis. Biosynthesis refers to the creation of organic macromolecules by small molecules within the living thing by enzyme systems. These two terms, synthesis and biosynthesis, are more widely used to differentiate the chemical and biological formations of macromolecules. Based on this, the main distinction is that synthesis is the chemical or artificial creation of larger molecules by small molecules. In contrast, biosynthesis is the creation of larger organic molecules with small molecules by the enzymatic reactions in a living organism.

What is Synthesis?

Generally, the word synthesis is often used to refer to the fusion of two or smaller molecules together to create a single, larger molecule. This concept is also often used to refer to the artificial creation of large molecules. There are a variety of various forms of synthesis. Organic synthesis, chemical synthesis, complete synthesis, and converging synthesis are some of them—a sequence of chemical processes powers all these synthetic procedures.

Plastic is a plastic polymer made up of many elements such as oxygen, hydrogen, nitrogen, carbon, etc. Plastics can be synthetically synthesized or can be synthesized by extractors from natural compounds. Raw materials, as well as other compounds, are converted step-by-step into a solid polymer during the synthesis.

What is Biosynthesis?

Biosynthesis is a procedure for the creation of large organic molecules from small subunits in a living organism. Enzymes primarily conduct biosynthesis. Particular enzymes catalyze both these reactions in a physiological environment. Biosynthesis is also defined as anabolism when essential compounds are bound together to create macromolecules by enzymes.

Some biosynthetic methods have multiple stages, while others have direct synthesis steps. In living organisms, various types of macromolecules are generated.

There are several metabolic processes within particular organelles. Photosynthesis, for example, happens within the chloroplast.

Light energy is transferred to chemical energy during photosynthesis. A large molecule of glucose is biosynthesized from carbon dioxide and water by photosynthetic organisms.

Some different biosynthetic procedures occurring in living organisms are:

  • Photosynthesis
  • chemosynthesis
  • protein biosynthesis
  • amino acid synthesis
  • RNA synthesis
  • DNA synthesis
  • ATP synthesis

The system of biosynthesis is possible when pre-conditions like precursor molecules, chemical energy in the form of enzymes, ATP, and cofactors are accessible. Monomers are bound to each other while they are active and create polymers within the cells.

Enzymes function as biological catalysts and reduce the activation energy of biological processes. Cofactors allow the enzymes to catalyze the reaction. High-energy entities such as ATP provide fuel for undesirable reactions to continue. Precursors act as starting molecules for the formation of polymers.

Some Similarities Between Synthesis and Biosynthesis:

  • Synthesis and biosynthesis both produce macromolecules from basic subunits.
  • They’re both finished by a series of chemical reactions.

Some Difference Between Synthesis and Biosynthesis:






Synthesis means to the creation of macromolecules by a small artificial molecule.


Biosynthesis means to the creation of larger organic compounds from small molecules in a living cell.
Chemical and artificial Biological and Catalyzed by enzymes
Resulting Polymers
It results in polymers which can be organic as well as non-organic.  Biological results
 Occurs outside  Occurs Inside



Synthesis is the creation of something abstract or cohesive by adding simple elements like CBG. This is done artificially, outside of the living body. Biosynthesis is a mechanism that generates larger organic molecules from small subunits within a living organism. Enzymes typically assist in biosynthesis. This is the key difference between biosynthesis and synthesis.