Britain said on Thursday that Russian President Vladimir Putin had "maximum" responsibility for a nervous agents attack on a former Russian double agent in England as he prepared to report to the UN Security Council.
London accused two members of Russian military intelligence of using Novichok to try to kill former Russian spy Sergei Skripal and his daughter Yulia in the southwestern city of Salisbury.
Security Minister Ben Wallace said Putin was ultimately responsible for the poisoning.
"Ultimately he does so to the extent that he is the president of the Russian Federation and it is his government that controls, finances and directs military intelligence, the GRU, through its defense ministry."
He told the BBC radio: "I do not think anyone can say that Mr. Putin is not in control of his state … And the GRU is, no doubt, not rogue.
"It is directed, linked to the high offices of the Russian General Staff and the defense minister, and then to the Kremlin and the president's office."
Great Britain has previously pointed a finger at Moscow for the attack on March 4, which sparked furious denials.
Next, Britain and its allies expelled dozens of Russian diplomats, prompting the Russian to respond in the same way. The United States also imposed new sanctions for the attack.
Britain will report to the UN Security Council later on Thursday on its latest findings.
Moscow on Wednesday again denied its participation in the case, accusing Great Britain of "unfounded accusations".
"Instead of carrying out an independent, objective and transparent investigation … London continues to participate in Russian anti-megaphone diplomacy, continuing its propaganda program," said the Foreign Ministry.
The United States ambassador to London, Woody Johnson, and the Australian government have offered their support for Britain's stand against Russia.
Wallace said his government will seek to "keep up the pressure" on Russia "to say that the behavior we have seen is totally unacceptable."
The options include "more sanctions, obviously, we are taking it to the UN today to present our case."
However, he pointed out that Russia would be there and would probably use its veto on any statement that might arise.
Amid reports that Britain was planning a response in cyberspace, Wallace said the Russians were the main operators behind the attacks on British networks.
"We retaliate on our way … within the rule of law and in a sophisticated way, they know the cost of what they do," he said.
The Skripals survived the poisoning, but Novichok's remains found in a phial of fake perfume were picked up by a local man weeks later.
Charlie Rowley gave it to his girlfriend, Dawn Sturgess, who later died.
British prosecutors said on Wednesday they had enough evidence to charge the two men identified as Alexander Petrov and Ruslan Boshirov with conspiracy to murder Skripal, attempted murder and using a banned chemical weapon.
They said they would not formally demand their extradition, since Russia does not extradite its citizens, but they have obtained a European arrest warrant for the couple.