Home Health The miracle Alzheimer’s drug Lecanemab, which can slow the disease, is to be approved for use in the UK in ‘the biggest breakthrough’ in decades

The miracle Alzheimer’s drug Lecanemab, which can slow the disease, is to be approved for use in the UK in ‘the biggest breakthrough’ in decades

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Alzheimer's disease affects 900,000 Britons (File image)

A wonder drug that can slow Alzheimer’s disease is to be approved for use in Britain.

Lecanemab is the first treatment that has been shown to slow the disease, slowing cognitive decline by 27 percent.

Experts have called it “the beginning of the end” of the disease, which affects around 900,000 Britons.

The Medicines and Healthcare products Regulatory Agency (MHRA) is set to approve the drug for private prescription in the UK.

The National Institute for Health and Care Excellence will then decide whether to roll out the treatment on the NHS.

Alzheimer’s disease affects 900,000 Britons (File image)

Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody drug used for the treatment of Alzheimer's disease.

Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody drug used for the treatment of Alzheimer’s disease.

Alzheimer's disease is the most common cause of dementia. The disease can cause anxiety, confusion and short-term memory loss.

Alzheimer’s disease is the most common cause of dementia. The disease can cause anxiety, confusion and short-term memory loss.

The drug, which is administered every two weeks through an intravenous drip, was approved in the United States last year.

However, last month the European Medicines Agency refused to authorise the drug due to concerns about side effects such as “swelling” and “possible bleeding in the brain”.

Professor John Hardy, from the UCL Institute of Neurology, described the drug as “the biggest breakthrough in Alzheimer’s in decades”.

He had previously hailed the “revolutionary” treatment as the “beginning of the end” of Alzheimer’s.

However, Dr Max Pemberton noted in his Daily Mail column last week that lecanemab – as well as another Alzheimer’s drug, donanemab – “is likely to produce only a small improvement in symptoms”.

The miracle Alzheimers drug Lecanemab which can slow the disease

The drug was found to slightly improve cognition, but could have significant side effects, according to a study published in the New England Journal of Medicine (File image)

A scientist collects a sample used for research into Alzheimer's disease.

A scientist collects a sample used for research into Alzheimer’s disease.

A study published in the New England Journal of Medicine last year found the drug slightly improved cognition but could have significant side effects.

An MHRA spokesperson told The Daily Telegraph: “We are currently completing a rigorous assessment of the evidence supporting lecanemab in the treatment of Alzheimer’s disease.”

They added that more information will be communicated “in due course”.

What is Alzheimer’s?

Alzheimer’s disease is a progressive, degenerative brain disease in which the accumulation of abnormal proteins causes nerve cells to die.

This disrupts the transmitters that carry messages and causes the brain to shrink.

More than 5 million people suffer from the disease in the United States, where it is the sixth leading cause of death, and more than a million Britons have it.

WHAT HAPPENS?

As brain cells die, the functions they provide are lost.

This includes memory, orientation, and the ability to think and reason.

The progression of the disease is slow and gradual.

On average, patients live five to seven years after diagnosis, but some may live ten to fifteen years.

EARLY SYMPTOMS:

  • Short-term memory loss
  • Disorientation
  • Behavioral changes
  • Mood swings
  • Difficulty handling money or making a phone call.

POSTERIOR SYMPTOMS:

  • Severe memory loss, forgetting close relatives, familiar objects or places.
  • Feeling anxious and frustrated by the inability to understand the world, leading to aggressive behavior.
  • Over time, the ability to walk is lost.
  • You may have trouble eating.
  • Most will eventually need 24-hour care.

Fountain: Alzheimer’s Association

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