Doctors have revealed the most common sites and types of rashes found in children with a rare coronavirus-related hyperinflammation.
Called MIS-C, patients were first diagnosed in 2020 after doctors noted that some children developed inflammation in a range of organs after exposure to SARS-CoV-2, with the Center for Disease Control saying it could be fatal, but most children survive.
Experts at Children’s Hospital in Philadelphia say diagnosing MIS-C has proven difficult because many of the symptoms, including rashes, fever, and gastrointestinal upset, are similar to other childhood conditions.
The team found that while there was no single location for rashes, they often occurred on the lower extremities, inner thigh, chest, and upper extremities.
In more than half of the seven patients studied, they usually presented as small to medium-sized circles the size of a 5 pence coin with small red spots in the center.
Authors hope that by highlighting common coronavirus rashes in children, their findings can help doctors and parents know when a rash needs further investigation.
Small 5p-sized plaques appear on the back of a child with MIS-C with small red spots on the inside
There was no single place where the rash appeared, and no single style for the rash – but researchers found they were common on arms and legs
COMMON RASH LOCATIONS AND SPECIES IN MIS-C
Researchers found that while there was no single location for rashes in children with MIS-C, there were some common placements and types.
A study of seven children with the condition helped researchers uncover some common trends.
All patients had a rash on their lower body, and five had a rash on their inner thighs, the team found.
Rashes on the chest and upper extremities were also common and occurred in four of seven patients.
More than half had small to medium sized ring-shaped plaques – UK 5p-sized circles on the chest and back.
More than half developed purpura – small red spots, often in the center of the small circular ring-shaped plaques.
Although some developed a cherry red rash on the bottoms of their feet and palms, this type of rash was seen in less than half of the patients.
A rash on the face was unusual and the rash was rarely itchy.
In April 2020, doctors began to recognize a syndrome in children with hyperinflammation that results in a range of symptoms.
These symptoms include the usual Covid-19 problems, including fever, as well as gastrointestinal upset and rashes.
The syndrome, thought to be a post-infectious complication of Covid-19, was dubbed Multisystem Inflammatory Syndrome Children or MIS-C.
However, diagnosing the condition posed challenges as many of the symptoms, including a rash, are common with many other childhood infections.
Philadelphia researchers say there was also no single type of rash or rash placement that was common in all the cases of MISH-C in the children they studied.
In a study published in Open Forum Infectious Diseases, researchers at Children’s Hospital of Philadelphia (CHOP) describe the range of rashes seen in MIS-C patients.
They say these are all seen in children with the condition and can hope that the photos they share in the newspaper can help doctors diagnose future cases.
“We hope that the information in this research letter will help general pediatricians and emergency physicians who may be wondering if a patient with a fever needs a more comprehensive examination,” said author Audrey Odom John.
“ Given that some rashes related to MIS-C are distinctive, we can also imagine that these images could help many parents looking for signs that their child needs a quick evaluation, ” explains CHOP’s infectious disease expert. from.
According to the team, all patients showed some degree of a rash on their lower extremities
One patient had a rash along the hairline – this was unusual, with the lower and upper limbs the most common sites for a rash
One patient saw a rash on the neck (left) and another saw a much larger rash on the shoulder (right), but both were uncommon and not found in all children
Regarding the site of the rash, all patients in the study developed a rash on their lower body and five of the seven patients had a rash on the inner thighs.
Rashes on the chest and upper extremities were also common, according to doctors, and occurred in four of seven patients.
More than half of the patients had small to medium sized ring-shaped plaques – circles the size of a UK 5p or US dime on the chest and back.
More than half of the patients in the study also developed purpura – small red spots, often in the center of the aforementioned small circular ring-shaped plaques.
Researchers have found a number of locations for the rash, including the stomach and legs
No two rashes were the same, some showing as several small dots and others as a few larger dots scattered across the abdomen, pouch, legs and arms
Although some patients developed a cherry red rash on the bottoms of their feet and palms, this type of rash was seen in less than half of the patients.
A rash on the face was unusual and the rash was rarely itchy.
“Depending on the age of the child, parents may not regularly look at the child’s chest, back, or thighs, but this is where the rash associated with MIS-C usually occurs,” said John.
“Since MIS-C is still largely a diagnosis of exclusion, parents and caregivers should look for a rash in these locations if the child has a fever that appears suspicious.”
The findings are published in the journal Open Forum Infectious Diseases
MISC-C (Multisystem Inflammatory Syndrome Children) is a rare condition related to SARS-CoV-2
In April 2020, doctors began noticing a condition in some children with the Coronavirus that resulted in a rash on their bodies at various points.
It involved hyperinflammation that resulted in a range of symptoms, including a rash, fever and gastrointestinal upset, doctors explained.
It is believed to be a post-infectious complication of the SARS-CoV-2 virus and has been called Multisystem Inflammatory Syndrome Children or MIS-C.
The CDC describes MISC-C as a condition in which various parts of the body can become inflamed – including the heart lungs, kidneys, brain, skin, and eyes.
The cause is not known, but the children with MISC-C also had SARS-CoV-2 or were close to someone with Covid-19.
It can be deadly, but most children who develop the condition were able to recover with medical care and hospital treatment, the CDC explained.
- Stomach ache
- Neck pain
- Bloodshot eyes
- Feeling extra tired
Diagnosing the condition proved difficult because the symptoms were similar to those in a range of childhood conditions – including the rash.
One study found that although there was no single rash, it was commonly found on the lower extremities, inner thigh, chest, and upper limbs.
The rash usually appears as a 5p circle with small red spots in the center.
The CDC says the best way to protect a child from MIS-C is to work to limit the entire household’s exposure to coronavirus by washing hands, taking social distance, and limiting how much you touch surfaces.