Pregnant women suffering from pre-eclampsia & # 039; are FIVE more likely to have kidney failure & # 039;

Pregnant women suffering from preeclampsia are FIVE times more likely to have kidney failure.

  • Research of more than 1 million women found pre-eclampsia increases the risk by 4.96 times
  • Both disorders are related to the breakdown of cells in the blood vessels
  • A mysterious genetic mutation can also increase the risk of both disorders

Pregnant women who suffer from preeclampsia are more likely to have kidney failure, research suggests.

Data from 1.3 million women showed expectant mothers fighting the complication are 4.96 times more likely if you have kidney disease at a later age.

Scientists from University College Cork, who led the study, admitted that they are currently unclear why the link exists.

But they noted that both disorders are related to the breakdown of cells that line the inside of blood vessels. A genetic mutation can also be to blame.


Pregnant women with pre-eclampsia are five times more likely to suffer from kidney failure (stock)

Pregnant women with pre-eclampsia are five times more likely to suffer from kidney failure (stock)

Preeclampsia is a pregnancy complication that causes high blood pressure and protein in the urine.

It affects up to six percent of pregnancies in the UK, according to the charity Tommy.

And in the US, five to eight percent of expectant mothers develop the condition, according to statistics from the Preeclampsia Foundation.

The condition, which can kill both mother and child, can only be cured by delivering the baby. Sufferers must be closely monitored until it is safe to do this.


Chronic kidney disease (CKD), also known as chronic renal failure, describes the gradual loss of kidney function.


Our kidneys filter waste products and excess fluids from the blood before they are excreted via urine. They also help maintain blood pressure.

As CKD progresses, the kidneys do not work properly and dangerous amounts of waste build up in your body.

The risk of CKD increases as you get older. It is also more common among Asians and Blacks.

CKD usually causes no symptoms until it has reached an advanced stage. It can be detected early through blood and urine tests.

Symptoms include:

  • Nausea
  • vomit
  • Loss of appetite
  • Fatigue and weakness
  • Sleep problems
  • Changes in how much you urinate
  • Decreased mental sharpness
  • Muscle vibrations and cramps
  • Swelling of feet and ankles
  • Persistent itching
  • Chest pain, as fluid accumulates around the inside of the heart
  • Shortness of breath, when fluid accumulates in the lungs
  • High blood pressure that is difficult to control

Those with the condition have a greater risk of stroke or heart attack. It can also cause kidney failure when patients require dialysis or a possible transplant.

However, lifestyle changes and medication can prevent the disease from getting worse if diagnosed at an early stage.

To reduce your risk:

  • Follow the instructions for freely available medicines. Taking too many painkillers can lead to kidney damage
  • Maintain a healthy weight
  • Do not smoke. Cigarette smoking can cause kidney damage

Source: Mayo Clinic

Kidney failure is the final phase of chronic kidney disease. It happens when the kidneys stop working well enough for a patient to survive without dialysis or a transplant.


About 61,000 people are being treated for kidney failure in the UK, according to statistics from Kidney Care UK.

And more than 660,000 Americans have the condition, according to the National Institute of Diabetes and Digestive and Kidney Diseases.

Kidney disease is increasing worldwide, the researchers wrote in the journal PLOS Medicine.

Early symptoms, such as swollen ankles, blood in the urine and itchy skin, are more common in women than in men.

This has led scientists to speculate whether there is pregnancy. To uncover this, the researchers analyzed data from the Swedish medical birth register.


They looked at more than 1.3 million women who gave birth more than 2.6 million times between 1982 and 2012.

Pre-eclampsia was recorded when the women were released from the hospital. They were then followed for a maximum of 30 years.

The results showed that women who had had preeclampsia in at least one pregnancy were nearly five times more likely to develop renal failure later in life.

And those who had two pregnancies complicated by pre-eclampsia were more than seven times more at risk.

This happened regardless of the woman's age or whether they had kidney or heart disease before they became pregnant.

The researchers estimate that pre-eclampsia is responsible for 14 percent of all cases of renal failure that affect mothers.

& # 39; Pre-eclampsia is a gender-specific, independent risk factor for the subsequent development of ESKD & # 39 ;, wrote the authors, led by Dr. Ali Kashan.

Preeclampsia was liked as a loss of specialized cells in the glomerulus. This is a cluster of capillaries in the kidneys that filter blood to produce urine.

This cell loss is not replenished after pregnancy and can increase a woman's renal failure, the researchers wrote.

However, they emphasized that & # 39; the total ESKD risk remains small & # 39 ;.


& # 39; Whether screening or preventative strategies will reduce the risk of ESKD in women with adverse pregnancy outcomes needs further investigation & # 39 ;, the researchers wrote.

Kim Kardashian developed pre-eclampsia during the pregnancy of her oldest daughter North West in 2012 to 2013.

To prevent complications that would affect both her and her unborn child, the then 32-year-old Kim was induced six weeks early.


Preeclampsia is a pregnancy complication that causes high blood pressure, which can be fatal to both a woman and her unborn baby if not treated.

It usually starts after 20 weeks of pregnancy in women whose blood pressure is normally normal.


The most effective treatment is an early birth; usually via C-section.

However, this may not be best for the baby if it is early in pregnancy.


Pre-eclampsia affects around 25,000 women in England and Wales and 4 percent of pregnancies in the US each year.

It can have no symptoms if it develops gradually instead of emerging suddenly.

A blood pressure measurement above 140/90 millimeters of mercury (mm Hg) on ​​two occasions is usually the first sign.


Other symptoms may include:

  • Severe headache
  • Blurred vision, temporary loss of vision or light sensitivity
  • Pain in the upper abdomen, especially under the ribs on the right
  • Nausea or vomiting
  • Decreased urination
  • Shortness of breath due to fluid retention in the lungs

Sudden weight gain and swelling in the face and hands are also symptoms, but these can occur during normal pregnancies.

It is thought that preeclampsia in the placenta starts when the blood vessels narrow and do not respond well to hormones.

This reduces the amount of blood that flows through it.

The underlying cause may be genetic, due to a problem with a woman's immune system or existing vascular damage.

A woman is more at risk if she, or a family member, has previously suffered from pre-eclampsia.

The risk is also highest during the first pregnancy, and if a woman is over 40; obese; black; have a multiple birth, such as twins; or conceived via IVF.

Existing medical conditions such as high blood pressure, diabetes, migraine and kidney diseases also increase the risk.

If it is not treated, pre-eclampsia can hamper the growth of a baby or cause it to be born early.

The placenta can also separate from the uterine wall, which can lead to serious bleeding.

A woman can also have epileptic seizures, organ damage and even heart disease as a result of untreated pre-eclampsia.

Although treatment usually leads to childbirth, medication can be prescribed to lower a woman's blood pressure if it is too early to give birth to the baby.

There is no clear advice on how to prevent pre-eclampsia, but research suggests that taking a low dose of aspirin and calcium supplements may help.

Pregnant women must talk to their doctor before taking medication or supplements.

Source: Mayo Clinic

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