Oprah Winfrey said that taking weight-loss medications, such as Ozempic and Wegovy, helped her realize the truth about “thin people.”
Last year, the media mogul, 70, finally admitted to using an undisclosed GLP-1 (a type 2 diabetes drug that can also help with weight loss) to lose nearly 50 pounds after decades of dieting. yo-yo.
The admission came as a surprise to fans, as Oprah had previously denied using weight loss medications and even went so far as to criticize the method as an “easy way out.”
But now, having almost reached her goal weight of 160 pounds, Winfrey shares her experience taking a GLP-1 and what it has taught her about the thin people she knows.
He did so while talking about the function and safety of this type of drugs with Dr. Ania Jastreboff in the last episode of his podcast.
“One of the things I realized the first time I took a GLP-1 was that all these years I thought that thin people had more willpower,” Winfrey confessed. ‘They ate better food. They were able to keep it up longer. They never ate French fries.
Oprah Winfrey said that taking weight-loss medications, such as Ozempic and Wegovy, helped her realize the truth about “thin people”; seen in December 2024
But once she started on a GLP-1, Winfrey realized that what she initially perceived as “willpower” was actually an absence of intrusive thoughts of hunger. often referred to as “food noise.”
Ozempic, Wegovy, and other GLP-1 medications can help eradicate food noise, which often leads to overeating and weight gain, by reducing cravings and slowing digestion.
“And then the first time I took the GLP-1, I realized they weren’t even thinking about it,” the billionaire said.
“They eat when they are hungry and stop eating when they are full.”
Winfrey explained that this way of eating ‘does not work’ if you fight obesity, which is a disease.
During her meeting with Dr. Jastreboff, Winfrey also spoke of being “publicly humiliated” for her weight throughout her decades-long career.
‘Every week (I was) exploited by the tabloids, every time a comedian wanted to make fun of it or make a joke about it, they would make a joke about it. And I accepted it because I thought I deserved it,’ he explained.
But now, Winfrey said she realizes that her size didn’t make her ‘less than’ anyone else and that she didn’t deserve that treatment.

He did so while talking about the function and safety of this type of drugs with Dr. Ania Jastreboff in the latest episode of her podcast.

Once she started on a GLP-1, Winfrey realized that what she initially perceived as “willpower” was actually an absence of intrusive thoughts of hunger, often referred to as “eating noise.”
Despite her initial denial about using weight-loss medications, Oprah declared she was “over the shame” in December 2023 when she revealed she used a GLP-1 to lose 40 pounds.
She also incorporated regular exercise, such as walking, to help her lose unwanted weight.
Winfrey told PEOPLE, “I use it now because I feel like I need it, as a tool to avoid yo-yoing,” but did not name the drug she uses.
“The fact that there is a medically approved prescription to control my weight and stay healthier throughout my life seems like a relief, a redemption, a gift, and not something to hide from and be ridiculed again.”
“I am absolutely sick of shaming other people and particularly myself,” adding that she had actively recommended weight loss help to others before deciding to take it herself.
The star revealed that she had taken the medication before Thanksgiving because she knew she would have “two weeks in a row of eating” and credits the medication for making her gain just half a pound instead of eight pounds, adding that it “calms down the noise of food.”
At the time, Winfrey said she was seven pounds shy of her goal weight of 160, but insisted “it’s not about the number.” Oprah weighed 237 pounds (107.5 kg) at her heaviest, she previously revealed.
He said undergoing knee surgery in 2021 began a journey to improve his health and live a “more vital and vibrant life.”

“And then the first time I took the GLP-1, I realized they weren’t even thinking about it,” he said. ‘They eat when they are hungry and stop eating when they are satisfied’


Last year, the media mogul (left in 2023 and right in 2019), 70, finally admitted to using an undisclosed GLP-1, a type 2 diabetes drug that can also help with weight loss, to lose almost 50 pounds after decades of exercise. -Me on a diet. The admission came as a surprise to fans, as Oprah initially denied using weight loss drugs to lose weight and even went so far as to criticize the method as an “easy way out.”
The streaming icon said he now eats his last meal at 4 p.m., drinks a gallon of water a day and uses WeightWatchers principles for counting points, along with regular walks.
She added that her fitness and health routine are key to maintaining her weight loss, saying, “It’s everything.” I know everyone thought I was in on this, but I worked really hard. I know that if I don’t exercise and I’m not paying attention to all the other things, it doesn’t work for me.’
She said: ‘I was aware of the (weight loss) medications but I felt I had to prove I had the willpower to do it. “Now I don’t feel that way anymore.”
Winfrey said she was encouraged to use medical medications to lose weight after the conversation recorded at a panel in July 2023 with doctors and weight loss experts, which led to her “biggest aha moment.”
The conversation was posted online in September and saw Winfrey flatly deny that she would ever take weight-loss medication.
She said: “I realized that I had been blaming myself all these years for being overweight and I have a predisposition that no amount of willpower is going to control.” Obesity is a disease. It’s not about willpower, it’s about the brain.
During the debate, experts insisted that obesity is a metabolic disease in which some bodies are “more predisposed to storing more fat,” also known as adipose tissue.
Oprah candidly explained, “For those of us who are fat storers, no matter how many times… You’ve all seen me diet and diet and diet and diet, it’s a recurring thing because my body always seems to want to go back.” up to a certain weight.

During her meeting with Dr. Jastreboff, Winfrey also spoke of being “publicly humiliated” for her weight throughout her decades-long career; seen in 1988
He added: “If I ate an apple pie at 11 at night, I would be two pounds heavier in the morning.” I can’t eat after a certain time.’
The television personality, who claimed to have “yoyoed my whole life,” later said: “This is a world that has shamed people for being overweight forever and all of us who have lived through it know that people just bully you. differently.” They just do it.
“And I’m Oprah Winfrey and I know what that entails and I’m treated differently if I’m over 200 pounds or under 200 pounds…
‘There is a condescension. There is a stigma.”
Oprah said the key was to have friends and partners around you who would offer support and “rejoice in your victory.”
After further discussion about the weight loss drugs currently available, including Ozempic and Wegovy, the media mogul said: “Shouldn’t we all be more accepting of whatever body you choose to have? That should be your choice.
“One of the things I was so embarrassed about, and even when I started hearing about weight-loss medications, at the same time I was having knee surgery and I felt, ‘I have to do this on my own body.’ “Because if I take the drug, that’s the easiest way out.”

Despite her initial denial about using weight-loss medications, Oprah declared she was “over with the shame” in December 2023 when she revealed that she used a GLP-1 to lose 40 pounds; seen in January 2024

‘I realized that I had been blaming myself all these years for being overweight and that I have a predisposition that no amount of willpower is going to control. Obesity is a disease. It’s not about willpower, it’s about the brain,’ he said; Winfrey seen in September 2024
“There’s a part of me that feels, as I think a lot of people feel with bariatric surgery, that I have to do it the hard way, I have to keep climbing mountains, I have to keep suffering. And I have to do it because otherwise , I somehow fooled myself.’
And she concluded: “As a person who has been shamed for so many years (for my weight), I am tired of it.”
The star said that after this talk, she released her ‘own shame’ and consulted her doctor, who prescribed her weight-loss medication.
Last year, she released the television documentary An Oprah Special: Shame, Blame and the Weight Loss Revolution, in which she appeared attacking those who shame people who turn to weight-loss medications.