Experts warn that “miracle” weight-loss drugs could lead to fractures and brittle bones.
Medications, such as Ozempic or Wegovy, can reduce body weight by 20 percent, but studies have found that they also have a long-term impact on bone density.
Research presented to the American Society for Bone and Mineral Research raised significant concerns about the potential side effects of these treatments.
One of the studies, published in the medical journal JAMA, evaluated 200 people using these medications and found that they had reduced bone mineral density in the hip and spine compared to a placebo or exercise alone.
This means that patients who receive weight-loss injections may be at higher risk for osteoporosis, a bone-thinning disease.
Experts have warned that ‘miracle’ weight loss drugs such as Ozempic and Wegovy could lead to fractures and brittle bones.
Research presented to the American Society for Bone and Mineral Research found that people using these medications had reduced bone mineral density in the hip and spine.
“The benefits of weight loss are undeniable, but the evidence also shows a loss of lean mass and bone density, which is concerning, particularly for patients with diseases such as osteoporosis, who are vulnerable to fractures,” says Dr. Taher Mahmud, founder of the London Osteoporosis Clinic.
“The data raise a concern for those people who already have an elevated risk of osteoporosis or fractures, such as those with obesity or type 2 diabetes.”
Ozempic and Wegovy are a type of drug known as a GLP-1 agonist, which reduces feelings of hunger.
Last week the Government announced that it would offer the drugs to the unemployed.
But experts say giving these injections to thousands of people could increase cases of osteoporosis, which can lead to dangerous bone fractures and falls.
Dr. Mahmud says it is critical for patients taking GLP-1 medications to exercise. ‘The importance of strength training, as well as cardiovascular exercise, should be promoted to help protect against loss of muscle and bone mass.
‘Tackling obesity is something we, as a nation, must address.
“But it is essential that we combine medicine with education and support to ensure that those taking GLP-1 agonists know the importance of good nutrition and weight-bearing exercise.”