May 3: Gerry and Kate McCann leave their three children, including Maddie, asleep in the apartment of their hotel in Praia da Luz, Portugal, while they eat with their friends at a nearby restaurant. When they return, they find Maddie missing from her bed
May 4: A friend of the McCanns reports that he saw a man carrying a child away at night. Meanwhile, airports and borders are put on high alert as the search goes live
May 14: Robert Mural, a property developer who lives a few meters from the hotel, is suspected by the Portuguese police
May 30: The McCanns meet with the Pope in Rome in an attempt to attract world attention to the search
August 11: Police in Spain acknowledge for the first time in the investigation that Maddie could be dead.
September 7: Spanish police turn the McCanns into official suspects of the disappearance. Two days later, the family flies back to England
July 21: Spanish police remove the McCanns and Mr. Mural as official suspects as the case is filed
May 1: The McCanns launch a computer-generated image of what Maddie would look like two years after her disappearance
May 12: Scotland Yard launches a review of the disappearance following a statement by the then Secretary of State, Theresa May.
April 25: After a year of review of the case, Scotland Yard announces that they believe that Maddie could be alive and calls on the police in Portugal to reopen the case, but falls on deaf ears in the midst of "lack of new tests"
Kate and Gerry McCann celebrate the fourth anniversary of the disappearance of their daughter Madeleine with the publication of the book written by her mother
July 4: Scotland Yard opens a new investigation and claims to have identified 38 & # 39; people of interest & # 39;
October 24: Portuguese police open a review of the investigation and new lines of investigation are discovered that force them to reopen the case
January 29: British officers arrive in Portugal when a detailed investigation is carried out. During the year, searches are made in several places, including a scrub area near the complex.
October 28: British police announce that the team investigating the disappearance of Maddie is reduced from 29 officers to only four, since it is also revealed that the investigation cost £ 10 million.
April 3: Theresa May gives Operation Grange an additional £ 95,000 to keep the investigation alive for another six months
March 11: Once again, money is injected to keep the investigation alive, with £ 85,000 granted to keep it going until September, when it is extended again until April next year.
March 27: The Ministry of the Interior reveals that it has allocated more funds to Operation Grange. It is believed that the new fund is as large as £ 150,000