An 11-year-old greyhound diagnosed with cancer in 2019 is now in remission and thriving thanks to a new vaccine.
Scientists at the University of Sydney treated the dog Kelly, using a sample of the tumor, allowing for personalized treatment.
This stimulates the patient’s immune system to fight cancer, a method also being developed to treat cancer in humans.
Kelly is one of 300 dogs who received an injection, which has been shown to not only rid the body of cancer, but also prevent it from recurring.
An 11-year-old greyhound (pictured) diagnosed with cancer in 2019 is now in remission and thriving thanks to a new vaccine
According to The Veterinary Cancer SocietyCancer is the leading cause of death in 47 percent of dogs, especially in dogs over 10 years of age.
And dogs develop cancer to the same degree as humans.
The vaccine was developed by the immunologist Dr. Christopher Weir of the University of Sydney, who has been working on the treatment for at least three years and was recently able to see the fruits of giving birth with Kelly.
Kelly’s owner, Jennifer Wiessel, saw lumps under her dog’s jaw in 2019, which were eventually diagnosed as lymphoma – an aggressive and fatal cancer in dogs.
Using a sample of the tumor allows for a personalized treatment that stimulates the patient’s immune system to fight the cancer, a method also being developed to treat cancer in humans
Like humans, Kelly underwent rounds of chemotherapy in the hope that radiation treatment would save her life.
However, Weissel knew her doting pet’s chances of surviving the deadly disease were slim, but that all changed when Kelly got Weir’s vaccine.
“Thanks to the first trial, we now know that the vaccine is safe,” said Dr. Weir in one statement.
“It seems to work for a variety of cancers – especially well with MAST cell tumors and lymphomas.”
Dr. Weir approached the vaccine as an immunotherapy, considered the most promising cure for cancer in humans.
In the dog, a biopsy of the tumor is removed, which is either frozen or processed immediately.
The sample is then combined with Advax, a solution that enhances the immune response of antibodies and T cells against co-administered antigens.
The treatment is much cheaper than chemotherapy, which can cost more than $ 10,000 per dog, according to the researcher.
However, the most promising results were found in dogs that had previously received chemotherapy prior to the vaccine.
While chemotherapy can only prolong survival, it usually doesn’t save the animal’s life, the University of Sydney shared in the statement.
Dr. Weir hopes his vaccine will eventually provide a cheaper, safer, and more effective treatment option. ‘
Jennifer Weissel (pictured) says the vaccine made her enjoy Kelly’s Golden Years she never thought her sweet pet would experience
Weissel says the vaccine made her enjoy Kelly’s Golden Years that she never thought her sweet pet would experience.
“I wasn’t going to do it because I was sure she wouldn’t live,” she said. ‘But it looks good now and she’s worth it … She’s family.
“I am grateful that we were given the opportunity to participate in this process. It has been a blessing. ‘
Kelly’s treatment is similar to what researchers at the Pritzker School of Molecular Engineering at the University of Chicago designed for humans.
The vaccine also uses the patient’s own tumor cells to program the immune system to find and attack cancer cells in the body.
The results were published March 24 in the journal Science Advances.
Prof. Melody Swartz, who led the study, said in a statement: “This is a new immunotherapy strategy.”
It has the potential to be more effective, cheaper, and much safer than many other immunotherapies. It is truly personalized medicine that has the potential to solve many of the problems that arise with other treatments. ‘
Larger breeds of dog, including Great Danes and Rottweilers, are at higher risk for LEG CANCER than smaller puppies, scientists warn
Osteosarcoma – a painful and aggressive form of bone cancer – is more common in larger dog breeds such as Great Danes and Rottweilers, a study has confirmed.
Experts led by the University of Bristol analyzed health data from 906,967 dogs to identify those breeds and characteristics that could increase the risk of cancer.
The team found that larger, heavier dogs and dogs with longer legs and skulls tend to be at greater risk of developing osteosarcoma.
The findings could pave the way for new therapies for dogs suffering from osteosarcoma, as well as help in treatments for bone cancer in humans.
“ There are growing concerns about the wisdom of breeding dogs with extreme body shapes, such as flat-faced breeds like French Bulldogs or long-backed breeds like Dachshunds, ” said paper author Dan O’Neill.
“This study highlights the health risks of another extreme body shape – a large body size,” added the Royal Veterinary College animal epidemiologist.