George Ford returns to England’s No.10 and forms a midfield partnership with Owen Farrell against Samoa.
Due to injuries and suspensions, Ford and Farrell have yet to start together under Steve Borthwick, but the experienced duo are likely to reunite for the final pool match in Lille.
England will announce their squad on Thursday and Manu Tuilagi is being publicly backed to make his first appearance against his ancestral homeland.
The center has never played against Samoa despite representing England for more than a decade, but that is set to change on Saturday.
Freddie Steward is likely to return at full-back, meaning Marcus Smith would miss the starting XV despite his exciting performance against Samoa.
George Ford returns at number 10 against Samoa and partner captain Owen Farrell in midfield

The experienced pair have already played together a number of times, but not yet under Steve Borthwick due to suspensions and injuries

Manu Tuilagi is about to start his first match against Samoa, the center’s ancestral homeland
Despite scoring five tries on his World Cup debut last week, winger Henry Arundell could also miss out.
Attack coach Richard Wigglesworth said: “It’s about balance. I’m not going to change the way Elliot Daly plays on the wing and try to get Henry Arundell to play like him, or the other way around, or for either of them. I want them to bring their best game to the field.”

The Borthwick side have already qualified for the last eight, where they are likely to face Fiji