Campaigners are calling for government support as figures show two pubs closing each day.
Two pubs a day disappeared in England and Wales during the first half of this year.
Some 383 pubs were demolished or converted for other uses, such as offices or homes, between January and June.
The total number of pubs in England and Wales, including those empty and rented, fell to 39,404 at the end of June.
Latest orders: The total number of pubs in England and Wales, including those vacant and rented, fell to 39,404 at the end of June.
Campaigners say the data, compiled by commercial real estate specialists Altus Group, underlines the need for the Government to support venues in the upcoming autumn budget.
UK Hospitality chief executive Kate Nicholls said: “These figures are a stark reminder of the reality facing pubs.
Businesses at the heart of communities gone forever, loyal staff losing their jobs and one less place for locals to eat and drink – this is the real cost of the economic upheaval many face.’
UK Hospitality is calling on the Government to extend business rates relief ahead of a “nearly £1bn” rates rise next April.