Manchester City will travel to Hungary on Wednesday to take on Borussia Monchengladbach, while Pep Guardiola wants to bring the domestic form of his side to Europe.
The Premier League leaders have been in inspired form since their 1-1 draw against West Brom in December, extending their winning streak to 18 in all competitions with a 1-0 win over Arsenal on Sunday.
They face a Mönchengladbach team struggling for form, having only won one of their last four matches.
The Germans, who finished fourth in the Bundesliga last season to qualify for the Champions League, are eighth this season, nine points lower than the qualifying places.
City are the big favorites expected to make it through a routine last-16 game, but their recent history in the league would tell you to expect the unexpected.
With the intriguing game lurking, Sportsmail takes you through the important information you need to know.
Pep Guardiola has led Manchester City to 18 consecutive wins in all competitions
Monchengladbach vs Man City: when and where is it?
The Champions League round of 16 first leg between Borussia Monchengladbach and Manchester City starts on Wednesday, February 24 at 8 p.m.
Although Mönchengladbach was drawn as the home side, complications from the coronavirus caused the match to move to Budapest in Hungary, with the Puskas Arena hosting the first match.
The return game at Etihad will then be played just under three weeks later, on March 16.
Monchengladbach vs Man City: how to watch
The meeting between Manchester City and Borussia Monchengladbach will be seen live on BT Sport.
Existing BT customers can watch the games on the television or stream them via the BT app or website.
Non-subscribers can also watch BT content through a monthly subscription for £ 25 without a contract.
Monchengladbach vs Man City: Team news
Kevin De Bruyne is fit to play for Manchester City after playing 63 minutes against Arsenal on Sunday
Manchester City have received a big boost with the return of Kevin De Bruyne, who started 63 minutes and played against Arsenal after his brief midweek cameo in their win over Everton.
The Belgian was out with a hamstring injury since January 20 and was eliminated early as he continued to build up to full fitness.
However, De Bruyne is planning to start a second game in a row as Pep Guardiola confirmed on Tuesday that he was not worried about new injuries.
The only remaining injury within the squad is from Nathan Ake, who last played in a Boxing Day win over Newcastle.
Meanwhile, Borussia Monchengladbach has no injuries within the squad, leaving manager Marco Rose plenty of options to think about.
Monchengladbach vs Man City: Champions League statistics
Group table: 2nd
Top scorer of the competition: Alassane Plea (5)
Goals against: 9
Clean sheets: 2
Distance traveled: 690.6 km
Passes Completed: 2,466
Group table: 1st
Top scorer: Ferran Torres (4)
Goals against: 1
Clean sheets: 5
Distance traveled: 654.2 km
Passes Completed: 3,683
The statistics above give a pretty clear picture of what the link between Borussia Monchengladbach and Manchester City will be like.
The German side had only 44 percent possession of the ball during their Champions League campaign, completed almost 1,000 passes less than City and ran almost 40 km more.
This will be a diligent effort by the home team, which you can guarantee that it will not go down without a fight.
However, there is also flair within Mönchengladbach, with the German side showing their relentless side on offense, scoring 16 goals in the group stage – three more than City.
The Premier League side has had much more ball possession with 59 percent, a pattern that will undoubtedly resurface on Wednesday.
In addition to their dominance on the ball, they also felt very comfortable in the back, conceding only one goal and keeping five clean sheets in six games.
Manchester City in the Champions League
Ferran Torres scored four goals in five matches in the Champions League group stage
As introductory above, City has been completely dominant in the Champions League so far this season.
The Premier League leaders have won five of the six games, with a lone draw against Porto the only mistake on an otherwise perfect group stage.
In actuality, City was not tasked with negotiating with the most challenging of groups, with Porto, Olympiacos and a sub-par Marseille completing the quartet.
Nonetheless, they completed the job in style, with Ferran Torres the star of the group stage in the summer, scoring in four different matches.
A win over Mönchengladbach would take them back to the Champions League quarter-finals, but it is the famous trophy they want so badly.
They just have to win the tie.
Borussia Monchengladbach in the Champions League
Alassane Plea claimed the match ball with a hat-trick in a 6-0 win over Shakhtar Donetsk
Borussia Monchengladbach had never reached the Champions League knockout stages before and was drawn into a significantly more challenging group than City.
In fact, they were arguably one of the surprising players in the Champions League of the past 16, despite taking domestic victories over Bayern Munich, RB Leipzig and Borussia Dortmund this season.
More surprising was that Inter Milan, which are now at the top of Serie A and reached the Europa League final last season, ended at the bottom of the group.
The quartet was completed by Shakhtar Donetsk and Real Madrid, progressing as group champions.
Monchengladbach closed the group with a record of two wins, two draws and two losses, identical to Shakhtar’s.
However, it was the German side that made progress, beating their group rivals in both home and away matches.
It was against Shakhtar where Monchengladbach produced their best performance to date in the league, with Alassane Plea scoring a hat-trick in a 6-0 demolition.
Monchengladbach vs Man City: the odds
With Manchester City currently in the midst of an absurd winning streak, it is no surprise that they are the overwhelming favorites for Wednesday’s game.
The Premier League leaders are preferred at 1/3 to win the match, while Mönchengladbach is the underdogs at 19/2, with a draw at 26/5.
* Odds courtesy of OddsChecker and correct at time of publication.