Painkillers, statins and fish oil can help heal or reduce depression in those who use them.
Anti-inflammatory drugs are nearly 80 percent more effective at eliminating depression than sugar pills, a scientific study has discovered.
The drugs, many of which are available without a prescription, are 52 percent better at reducing symptoms of depression.
Experts believe they work by reducing inflammation, which is the body's response to things like stress and a poor diet, and can cause brain depression.
However, the conclusion is based on an assessment of only four studies of a painkiller used for arthritis and three studies of statins.
Experts believe that the drugs work by reducing inflammation, which is the body's response to things such as stress and a poor diet, and can cause brain depression (stock)
A total of 26 studies were viewed, including more than 1,600 people, who mainly took omega-3 supplements, such as fish oil pills, but also other anti-inflammatory drugs such as steroids and antibiotics.
The authors of the review, led by Huazhong University of Science and Technology in China, wrote: & # 39; The results of this systematic review suggest that anti-inflammatory drugs play an antidepressant role in patients with major depressive disorder and are reasonably safe. & # 39;
Professor Ed Bullmore, head of the psychiatry department at Cambridge University, who was not involved in the study, said: & # 39; This should encourage further consideration of how we can use a series of anti-inflammatory interventions to help people with depression, perhaps especially people who already use a conventional antidepressant with limited benefit.
& # 39; However, as the authors conclude, further tests will be needed to support licenses and medical prescriptions for this and other anti-inflammatory drugs for depression. & # 39;
Almost a third of people with depression are unable to get out, even with the various antidepressants and counseling available.
The assessment suggests that taking anti-inflammatory drugs, especially at the same time as antidepressants, may help.
Anti-inflammatory drugs, such as aspirin, are nearly 80 percent more effective at eliminating depression than sugar pills, a scientific study has shown
WHAT IS DEPRESSION?
Although it is normal to feel down from time to time, people with depression may remain unhappy for weeks or months.
Depression can affect anyone at any age and is fairly common – about one in ten people is likely to experience it at some point in their lives.
Depression is a real health condition that people cannot simply ignore or break out & # 39 ;.
Symptoms and effects vary, but can also be that you constantly feel upset or hopeless, or that you lose interest in things you used to like.
It can also cause physical symptoms such as sleeping problems, fatigue, low appetite or sex drive, and even physical pain.
In extreme cases this can lead to suicidal thoughts.
Traumatic events can cause this and people with a family history are more at risk.
It is important to consult a doctor if you think that you or someone you know has depression because it can be managed with changes in lifestyle, therapy or medication.
Source: NHS Choices
In the 26 studies, anti-inflammatory drugs, including the sleeping pill modafinil and a drug for cystic fibrosis, were 79 percent better than a placebo in curing depression.
A course of medication, usually six to 12 weeks, turned out to be more than half as good as a placebo for reducing depression symptoms.
There is increasing evidence that anti-inflammatory drugs can help with feelings of accident and hopelessness, because people with depression have linked higher levels of chemicals in their blood to inflammation.
This inflammation is the body's stress response to environmental factors such as pollution, alcohol and smoking, and when it persists over time, it is believed to affect the way emotions are regulated in the brain.
The best results in the review were seen in people taking omega-3 pills, statins, antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and ibuprofen.
However, the review did not look at aspirin and ibuprofen, but only at celexocib, which is mainly used as a painkiller for patients with arthritis.
The results suggest that statins and antibiotics can help with depression, are based on a total of six studies, where 166 and 151 people were viewed.
A clear suggestion from the study, based on 22 of the 26 studies, is that anti-inflammatory drugs can help when used with antidepressants.
But the researchers, whose work is published in the Journal of Neurology, Neurosurgery and Psychiatry, discovered that these drugs had no significant effect on women in women-only studies that might be related to female hormones.
The assessment states that people taking anti-inflammatory drugs did not have major side effects, although there were some bowel problems.
Professor David Curtis, honorary professor at University College London, who was also not involved in the study, said: & # 39; It is quite misleading to describe the use of anti-inflammatory drugs as safe.
& # 39; The most effective anti-inflammatory drugs that were used were NSAID & although problems are rare, thousands of people die each year from the side effects of these drugs, which are usually used for chronic pain and are especially dangerous if they are taken for a long time. & # 39;
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