Having a figure in the shape of an apple can increase a woman's risk of brain damage.
The storage of fat around his abdomen, like the comedian Amy Schumer or the singer Jessica Simpson, could trigger an inflammation that reaches the brain and causes life-changing injuries, according to a US study.
Apple figures generally cause women to carry weight around their waists, which are wider than their hips. Such physicists have been associated with excess storage of fat around the internal organs.
In contrast, pear-shaped women, such as television personality Kim Kardashian, store weight in the hips, thighs or buttocks and have less risk of diseases such as type 2 diabetes or heart disease.
The lead author, Professor Djurdjica Coss of the University of California at Riverside, said: "My advice is:" Watch your diet! "And monitor body weight, especially around the abdomen."
Actress and comedian Amy Schumer has an apple-shaped figure because of her weight around her waist, which is wider than her hips. Such physicists have been associated with the storage of excess fat around the internal organs and now even the inflammation of the brain
Pear-shaped women, such as television personality Kim Kardashian, store weight in their hips, thighs or buttocks and have less risk of diseases such as type 2 diabetes or heart disease.
DO YOU HAVE AN APPLE-SHAPED FIGURE RAIZE THE RISK OF A WOMAN FROM A CARDIAC ATTACK?
Having an apple-shaped figure increases a woman's risk of having a heart attack by up to 20 percent, an investigation suggested in February 2018.
Even among skinny women, like the famous Elizabeth Hurley, Angelina Jolie and Tyra Banks, carrying fat around the abdomen makes them 10 to 20 percent more likely to suffer a cardiovascular event, according to a study.
The lead author, Dr. Sanne Peters of the University of Oxford, said: "Our findings support the idea that having proportionally more fat around the abdomen (a feature of the apple's shape) seems to be more dangerous than fat. visceral that is usually stored around the hips (ie, the pear shape).
The researchers analyzed 479,610 adults aged 40 to 69 who participated in the Biobank study in the United Kingdom between 2006 and 2010.
The trained personnel measured the waist and hip circumferences of the participants in the study, as well as their height, weight and BMI.
According to the researchers, more research is needed to determine how body shape and fat storage influence people's heart disease risk.
The findings were published in the Journal of the American Heart Association.
The researchers analyzed three-week-old male mice. Like men, male rodents tend to store fat around their abdomen, creating an apple shape.
They also observed female mice, which typically deposit fat around their hips, like women.
Some of the animals were fed a high-fat diet while others had a standard diet.
Blood samples were taken from all the mice to determine how their diets affected their hormonal levels.
The results suggest that obese male rats store fat in their abdomens, creating an apple shape.
Such rodents also have higher levels of inflammation in their brains.
Obese rats, however, store excess fat under the skin and have a lower amount of inflammation.
Professor Coss said: "We know that the abdominal fat, that is, the fat around the visceral organs, becomes more inflamed with an overload of fat.
"This fat then recruits immune cells from the bloodstream that are activated."
In obese male mice, these immune cells even cross the blood-brain barrier, which generally protects dangerous substances from reaching the vital organ.
Professor Coss said: "The brain has been considered a" protected immune site, "but we show that peripheral inflammation" spills "into the brain, which in turn can cause neuronal problems."
Long-term brain inflammation has previously been associated with organ damage.
The singer and fashion designer Jessica Simpson also has a figure in the shape of an apple. The new study found that mice with the same fat storage have higher levels of inflammation, which even crosses the blood-brain barrier. This barrier is usually able to keep dangerous substances out of danger
In addition to the higher levels of inflammation, obese male mice are also more likely to develop metabolic syndrome than their female counterparts.
Metabolic syndrome occurs when a person has at least three of the following: abdominal obesity, high blood pressure, high blood sugar, large amounts of blood fat and high cholesterol.
Professor Coss said: "Mice with a high-fat diet develop the metabolic syndrome, a constellation of pathologies that includes type 2 diabetes and insulin insensitivity, similar to obese humans.
"Obese men have lower testosterone levels, which contributes to low libido, low energy and reduced muscle strength, and we see this in mice, too: obese male mice showed almost a 50 percent decrease in the number of testosterone and sperm & # 39;
In addition, when female mice are fed the same high-fat diet as males, it takes longer to gain weight.
It is believed that this is due to female mice that produce estrogen, which protects them from weight gain. Many women gain weight after menopause due to a decrease in this hormone.
When the researchers removed the ovaries from the rodents to simulate menopause, the female mice gained weight but did not experience the inflammation seen in obese men.
This suggests that other factors besides estrogen may protect against the effects of obesity in female mice.
However, when obese females continued to gain weight, their fat storage changed to their abdomen, making them apple-shaped.
Professor Coss said: "While being overweight, women are more protected than men when it comes to inflammation.
"This protection is significantly reduced when overweight women become obese and fat accumulates around the waist."